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Compared before and after administration of MgSO4, T-Mg and I-Mg levels and T-Ca levels were changed allow statistically significant (P0.05). There was no significant difference in T-Ca and I-Ca levels during MgSO4 administration (P>0.05). Statistical difference between ionized calcium level in NS and in healthy children was significant (P0.05). The mean ionized calcium and serum albumin level in NS children was 4.56 (SD 0.23 mg/dLand 1.45 (SD 0.24 g/dL, respectively. Results A total of34 subjects were recruited, consist of 17 NS and 17 healthy children. Ionized calcium was examined by Ca2 + analyzer AVL 980 with ion-selective electrodes (ISE methods. Methods An analytical study with cross-sectional design was applied to NS and healthy children between 1-14 years old in the Child Health Department of Hasan Sadikin Hospital, Bandung from December 2009 to April 2010. Objective To assess the rel ationship between ionized calcium and serum albumin level in idiopathic NS children. The ionized calcium level depends on the severity and duration of proteinuria. Hypocalcemia is initially attributed to hypoalbuminemia but it may also relate to a low level of ionized calcium. Relationship between ionized calcium and serum albumin level in children with idiopathic nephrotic syndromeĭirectory of Open Access Journals (Sweden)įull Text Available Background Nephrotic syndrome (NS patients frequently have abnormalities in calcium metabolism that manifest as hypocalcemia and reduced intestinal absorption of calcium. Generally, people should be advised to avoid direct contact with infected body fluids and tissues. Preventive measures include informing people when zoonotic plague is present in their environment and advising them to take precautions against flea bites and not to handle animal carcasses. 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